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Alprostadil acts locally to increase penile blood flow. Onset and duration vary between individuals, and the prescribed starting dose may need adjustment for tolerability. It does not permanently correct the cause of erectile dysfunction.

How to use it

Each container is used once, in a fixed order. Read this through before the first application rather than during it.
1

Apply one prescribed single-use container

Urinate first, wash hands, then place the cream at the opening on the tip of the penis exactly as shown in the leaflet. Hold the penis upright for about 30 seconds so the cream can enter. Do not insert the applicator into the urethra.
2

Use once and discard

Each AccuDose container is for one application. Do not use a second container to replace cream that remains at the opening. Wash hands after use, and do not urinate immediately afterwards.

Dose schedule

Five to thirty minutes before sex

The effect may begin within 5–30 minutes and can last about 1–2 hours, with individual variation.

Maximum frequency

Do not use more than once in 24 hours, or more than 2–3 times per week. Do not combine with another erectile-dysfunction treatment unless the prescriber has explicitly planned it.

What has been reported

Contact your doctor if

  • An erection lasts 4 hours or longer, is very painful, or does not settle — seek emergency care
  • Fainting, chest symptoms, heavy urethral bleeding, marked swelling, or a severe allergic reaction
  • Local pain or partner irritation is persistent, or the dose needs adjustment
An erection lasting 4 hours or longer, or one that is very painful or does not settle, needs emergency care.

Storage

Keep unopened sachets refrigerated at 2–8°C and do not freeze. A sachet may be kept below 25°C for up to 3 days before use — discard it if not used within that time. Protect from light and use immediately after opening.

What to expect

A licensed EU doctor will review your case in under 24 hours. Because alprostadil does not permanently correct the underlying cause of erectile dysfunction, the doctor may also discuss oral options.

Common questions

Alprostadil is a copy of prostaglandin E1, a substance the body makes naturally that widens blood vessels. Applied to the tip of the penis, it relaxes the smooth muscle of the corpora cavernosa and widens the arteries feeding them, increasing blood flow. Because it acts directly on the blood vessels, it does not depend on sexual arousal in the way PDE5 tablets do.
The effect may begin within 5 to 30 minutes and can last about 1 to 2 hours, with individual variation. Use the prescribed dose as needed, up to once in 24 hours and no more than 2 to 3 times per week.
Do not combine Vitaros with another erectile-dysfunction treatment unless the prescriber has explicitly planned it. The doctor may discuss oral PDE5 inhibitors such as vardenafil or avanafil as alternatives.
Penile burning, pain, redness, tingling, swelling or genital discomfort can occur. A partner may also experience burning or irritation after contact. Dizziness or faintness can occur. An erection lasting 4 hours or longer needs emergency care.
Keep unopened sachets refrigerated at 2 to 8°C and do not freeze. A sachet may be kept below 25°C for up to 3 days before use. Discard it if not used within that time. Protect from light and use immediately after opening.

How Hi-Doctor handles it

Related reading: vardenafil (Levitra) and avanafil (Spedra), the oral PDE5-inhibitor alternatives a doctor may consider instead. See also safety and eligibility checks and how a Hi-Doctor consultation works.

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Sexual health consultation

Answer the sexual health questionnaire and a registered doctor reviews it. They decide whether treatment is appropriate, which one, and at what dose — and declining is a normal outcome. See what it costs and how the review works.
This page is reference information, not medical advice and not a prescription. Whether a medicine is appropriate for you is decided by a registered doctor after reviewing your consultation.