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Mounjaro contains tirzepatide and is given as one injection under the skin, once a week, on the same day each week. This page covers handling the pen. The dose and the schedule belong to the doctor who reviewed your consultation.
The patient information leaflet packed with your own pen, and the instructions your doctor gave you, override everything on this page. Pen designs, needle types and dose steps differ between products and between presentations of the same product. If the two disagree, follow the leaflet and your doctor, and message the medical team.

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What Mounjaro is

Mounjaro is a once-weekly injection for weight management. It copies two gut hormones — GIP and GLP-1 — which together reduce appetite, slow how quickly your stomach empties, and help steady your blood sugar. The EMA marketing authorisation has been valid across the EU since 15 September 2022 under EMEA/H/C/005620, and one central authorisation covers all 27 member states. Alongside the single-dose pre-filled pen, the Spanish register also lists multi-dose KwikPen and vial presentations at every strength — so check which one you actually hold before following any instruction.

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Injecting

The injection itself is a fixed sequence. Work through it in this order every week, and check each step against your own leaflet the first few times.
1

Wash your hands and check the pen

Check the label, the expiry date and the liquid. If it does not look the way your leaflet describes, do not use that pen.
2

Attach a new needle

A fresh needle every time, if your presentation uses separate needles. Needles are single-use.
3

Choose and rotate the injection site

Rotate between abdomen, thigh or upper arm each week. Clean the area with an alcohol swab and let it dry.
4

Inject just under the skin

Mounjaro is injected subcutaneously. Do not inject into a vein or muscle.
5

Hold it in place for 5 seconds after the click

The injection pen delivers the full dose — keep it still against the skin for 5 seconds after the click.
6

Remove the needle and dispose of it safely

Put it straight into a sharps container and never reuse it. See injection sites and sharps disposal.

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Pick a day and keep it

Inject on the same day each week. Pick a day that works for you. If you forget a dose, take it within 4 days of the missed dose. If more than 4 days have passed, skip that dose and take your next one on the regular scheduled day. More in missed or late doses.

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The published dose schedule

Tirzepatide is dosed at 2.5 – 15 mg per week. The published escalation is:
This is the published ladder, not an instruction. It is a chronic treatment for as long as it is beneficial and safe: the doctor reviews your response every 3 months and decides with you whether to continue, adjust or stop.

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Storage

Store unused pens in the refrigerator (2–8°C). Once opened, keep at room temperature below 30°C for up to 30 days. Do not freeze. Keep away from direct heat and light.

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Contact your doctor if

  • severe or persistent nausea, vomiting or diarrhoea prevents you from eating or drinking
  • you have severe abdominal pain that does not go away
  • you notice signs of an allergic reaction — rash, itching, swelling of the face or throat
  • any symptom worries you or feels unusual
For severe, sudden or unexpected symptoms, call your local emergency number first — see Safety. Related: Mounjaro · tirzepatide · what to expect in the first month · how a consultation works · safety and eligibility

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Start a consultation

Weight-loss consultation

Answer the weight-loss questionnaire and a registered doctor reviews it. They decide whether treatment is appropriate, which one, and at what dose — and declining is a normal outcome. See what it costs and how the review works.
This page is reference information, not medical advice and not a prescription. Whether a medicine is appropriate for you is decided by a registered doctor after reviewing your consultation.